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日期:2016-10-13 16:04

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(35) A metabolic labeling method detects m6A transcriptome-wide at single base resolution

Shu, X.; Cao, J.; Cheng, M.H.; Xiang, S.Y.; Gao, M.S.; Li, T.; Ying, X.E.; Wang, F.Q.; Yue, Y.N.; Lu, Z.K.; Dai, Q.;  Cui, X.L.; Ma, L.J.; Wang, Y.Z.; He, C.; Feng, X.H. and Liu, J.Z.*. Nature Chemical Biology. 2020. DOI: 10.1038/s41589-020-0526-9

(Highlighted by Nature Reviews Genetics "New tools for transcriptome-wide mapping of m6A", DOI: https://doi.org/10.1038/s41576-020-0248-6)

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(34) N6-Deoxyadenosine Methylation in Mammalian Mitochondrial DNA

Hao, Z.Y.; Wu, T.; Cui, X.L.; Zhu, P.P.; Tan, C.P.; Dou, X.Y.; Hsu, K.W.; Lin, Y.T.; Peng, P.H.; Zhang, L.S.; Gao, Y.W.; Hu, L.L.; Sun, H.L.; Zhu, A.; Liu, J.Z.;Wu, K.J. and He, C.*. Molecular Cell. 2020, DOI:10.1016/j.molcel.2020.02.018.

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(33) Visualization and quantification of cellular RNA production and degradation using a fluorescence and mass spectrometrycombined characterization assay

 Gao, X.Y.; Shu, X.; Song, Y.N.; Cao, J.; Gao, M.S.; Wang, F.Q.; Wang, Y.Z.; Sun, J.Z.; Liu, J.Z. * and Tang, B.Z. *Chem. Commun.2019, DOI:10.1039/C9CC03923F.

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(32) RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail
Lin, X.Y.; Chai, S.G.; Wu, Y.M.; Li, J.X.; Chen, F.; Liu, J.Z.; Luo, G.Z.; Tauler, J.; Du, J.; Lin, S.B.; He, C. & Wang, H.S.* . Nature Communications. 2019 . 10:2065, DOI: 10.1038/s41467-019-09865-9 

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(31) Specific Targeting, Imaging, and Ablation of Tumor-Associated Macrophages by Theranostic Mannose–AIEgen Conjugates
Gao, X.Y.; Mao, D.; Zuo, X.G.; Hu, F.; Cao, J.; Zhang, P.; Sun, J.Z.; Liu, J.Z.*; Liu, B.*; Tang, B.Z.*. Analytical Chemistry. 2019 ,91,6836-6843.

(30) Circadian Clock Regulation of Hepatic Lipid Metabolism by Modulation of m6A mRNA Methylation
Zhong, X.; Yu, J.Y.; Frazier, K.Y.; Weng, X.C.; Li, Y.; Cham, C.M.; Dolan, K.; Zhu, X.R.; Hubert, N.; Tao, Y.; Guryn, K.M,; Huang, Y.; Wang, T.; Liu, J.Z.; He, C.; Chang, E.B.; Leone, V. Cell Reports. 2018, 25(7), 1816–1828.

(29) m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer
Liu, J.; Eckert, M. A.; Harada, B. T.; Liu, S. M.; Lu, Z. K.; Yu, K. K.; Tienda, S. M.; Chryplewicz, A.; Zhu, A. C.; Yang, Y.; Huang, J. T.; Chen, S. M.; Xu, Z. G.; Leng, X. H.; Yu, X. C.; Cao, J.; Zhang, Z. Z.; Liu, J. Z.; Lengyel, E.*; He, C.*. Nature Cell Biology. 2018, 20, 1074–1083.

(28)  Biochromic silole derivatives: a single dye for differentiation, quantitation and imaging of live/dead cells
Chen, S. J.; Liu, J. Z.; Zhang, S. Z.; Zhao, E. G.; Yu, Y. Y. C.; Hushiarian, R.; Hong, Y. N.* and Tang, B. Z.* Mater. Horiz. 2018, 5, 969-978.

(27) A unimolecular theranostic system with H2O2-specific response and AIE-activity for doxorubicin releasing and real-time tracking in living cells
Gao, X. Y.; Cao, J. ; Song, Y. N ; Shu, X. ; Liu, J. Z;* Sun, J. Z ; Liu, B. ;* Tang, B. Z*.
RSC Advances. 2018, 8, 10975-10979.

(26)  VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon  and associates with alternative polyadenylation
Yue, Y.; Liu, J.; Cui, X.;Cao, J.;Luo, G.; Zhang, Z.; Cheng, T.; Gao, M.; Shu, X.; Ma, H.; Wang, F.; Wang, X.; Shen, B.; Wang, Y.; Feng, X.; He, C.*& Liu, J. Z.*. Cell Discovery, 2018, 4, 10.

(25)  N6-Allyladenosine: a New Small Molecule for RNA Labeling Identified by Mutation Assay
Shu, X.; Dai, Q.;Wu, T.; Bothwell, I. R.; Yue, Y.; Zhang, Z.; Cao, J.; Fei, Q.; Luo, M.; He, C*.; Liu, J. Z*.; J. Am. Chem. Soc. 2017,139 (48), 17213–17216


(24) A Two-Channel Responsive Fluorescent Probe with AIE Characteristics and Its Application for Selective Imaging of Superoxide Anions in Living Cells
Gao, X,Y.; Feng, G.; Manghnani, P. N.; Hu, F.; Jiang, N.; Liu, J. Z. ; Liu, B*.; Sun, J. Z*.; Tang, B. Z*. Chem. Commun 2017, 53, 1653-1656.

Pre-ZJU(Selected publications)


(23) Abundant DNA 6mA Methylation during Early Embryogenesis of Zebrafish and Pig
Liu, J. Z.; Zhu, Y.; Luo, G. Z.; Yue, Y. N.; Wang, X. N.; Zong, X.; Chen, K.; Yin, H.; Fu, Y.; Han, D. L.; Wang, Y. Z*.; Chen, D. H*.; He, C*. Nat. Commun .2016, 7.

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(22) Characterization of Eukaryotic DNA N6-Methyladenine by a Highly Sensitive estriction Enzyme-Assisted Sequencing
Luo, G. Z.; Wang, F.; Weng, X. C.; Chen, K.; Hao, Z. Y.; Yu, M.; Deng, X.; Liu, J. Z. ; He, C.; Nat. Commun 2016, 7, 11301.

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(21) N6-Methyladenine DNA Modification in Drosophila
Zhang, G.; Huang, H.; Liu, D.; Cheng, Y.; Liu, X.; Zhang, W.; Yin, R.; Zhang, D.; Zhang, P.; Liu, J. Z.; Li, C.; Liu, B.; Luo, Y.; Zhu, Y.; Zhang, N.; He, S.; He, C.; Wang, H.; Chen, D. Cell, 2015, 161, 893-906.

(20) DNA Methylation on N6-Adenine in C. elegans
Greer, Eric L.; Blanco, Mario A.; Gu, L.; Sendinc, E.; Liu, J. Z.; Aristizábal-Corrales, D.; Hsu, C.-H.; Aravind, L.; He, C.; Shi, Y. Cell, 2015,161, 868-878.

(19) N6-Methyldeoxyadenosine Marks Active Transcription Start Sites in Chlamydomonas
Fu, Y.; Luo, G.-Z.; Chen, K.; Deng, X.; Yu, M.; Han, D.; Hao, Z.; Liu, J. Z.; Lu, X.; Doré, Louis C.; Weng, X.; Ji, Q.; Mets, L.; He, C. Cell, 2015,161, 879-892.

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(18) RNA N6-Methyladenosine Methylation in Post-transcriptional Gene Expression Regulation
Yue, Y.; Liu, J. Z.; He, C. Genes Dev. 2015, 29, 1343-1355.

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(17) A METTL3-METTL14 Complex Mediates Mammalian Nuclear RNA N-6-Adenosine Methylation 

Liu, J. Z. ;Yue, Y. ; ; Han, D.; Wang, X.; Fu, Y.; Zhang, L.; Jia, G.; Yu, M.; Lu, Z.; Deng, X.; Dai, Q.; Chen, W.; He, C. Nat. Chem. Biol. 2014, 10, 93-95 (†contributed equally).

(16) A Protein Engineered to Bind Uranyl Selectively and with Femtomolar Affinity
Zhou, L.; Bosscher, M.; Zhang, C.; Özçubukçu, S.; Zhang, L.; Zhang, W.; Li, C. J.; Liu, J. Z.; Jensen, M. P.; Lai, L.; He, C. Nat. Chem. 2014, 6, 236-241.

(15) Direct Visualization of   Surface-Assisted Two-Dimensional Diyne Polycyclotrimerization
Zhou, H.; Liu, J. Z.; Du, S.; Zhang, L.; Li, G.; Zhang, Y.; Tang, B. Z.; Gao,   H. J. Am. Chem. Soc. 2014,136, 5567-5570. (†contributed equally).

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(14) Full-Range Intracellular pH Sensing by an Aggregation-Induced Emission-Active Two-Channel Ratiometric Fluorogen
Chen, S.; Hong, Y.; Liu, Y.; Liu, J. Z.; Leung, C. W. T.; Li, M.; Kwok, R. T. K.; Zhao, E.; Lam, J. W. Y.; Yu, Y.; Tang, B. Z. J. Am. Chem. Soc. 2013,135, 4926-4929.

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(13) Real-Time Monitoring of Cell Apoptosis and Drug Screening Using Fluorescent Light-up Probe with Aggregation-Induced Emission Characteristics
Shi, H.; Kowk, R. T. K.; Liu, J. Z.; Xing, B.; Tang, B. Z.; Liu, B. J. Am. Chem. Soc. 2012, 34, 17972-17981.

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(12) Specific Detection of Integrin αvβ3 by Light-up Bioprobe with Aggregation-Induced Emission Characteristics
Shi, H.; Liu, J. Z.; Geng, J.; Tang, B. Z.; Liu, B. J. Am. Chem. Soc. 2012, 134, 9569-9572.

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(11) Monitoring and Inhibition of Insulin Fibrillation by a Small Organic Fluorogen with Aggregation-Induced Emission Characteristics
Hong, Y.; Meng, L.; Chen, S.; Leung, C. W. T.; Da, L.; Mahtab, F.; Silva Manzano, D.; Liu, J. Z.; Lam, J. W. Y.; Huang, X.; Tang, B. Z. J. Am. Chem. Soc. 2012,134,1680-1689.

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(10) What Makes Efficient Circularly Polarized Luminescence in Condensed Phase: Aggregation-Induced Dichroism and Light Emission
Liu, J. Z.; Su, H.; Meng, L.; Zhao, Y.; Deng, C.; Ng, J. C. Y.; Lu, P.; Faisal, M.; Lam, J. W. Y.; Huang, X.; Wu, H.; Wong, K. S.; Tang, B. Z. Chem. Sci. 2012,3, 2737-2747.

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(9) An AIE-Active Hemicyanine Fluorogen with Stimuli-Responsive Red/Blue Emission: Extending the pH Sensing Range by “Switch + Knob” Effect
Chen, S. ;Liu, J. Z; Liu, Y.; Su, H.; Hong, Y.; Jim, C. K. W.; Kwok, R. T. K.; Zhao, N.; Qin, W.; Lam, J. W. Y.; Wong, K. S.; Tang, B. Z. Chem. Sci. 2012,3, 1804-1809 (†contributed equally).

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(8) Deciphering Mechanism of Aggregation-Induced Emission (AIE): Is E–Z Isomerization Involved in an AIE Process?
Tseng, N. ;Liu, J. Z.; Ng, J. C. Y.; Lam, J. W. Y.; Sung, H. Y.; Williams, I. D.; Tang, B. Z. Chem. Sci. 2012, 3, 493-497 (†contributed equally).

(7) A New Polymerization Route to Conjugated Polymers: Regio- and Stereoselective Synthesis of Linear and Hyperbranched Poly(arylene chlorovinylene)s by Decarbonylative Polyaddition of Aroyl Chlorides and Alkynes
Liu, J. Z.; Deng, C.; Tseng, N. W.; Chan, C. Y. K.; Yue, Y.; Ng, J. C. Y.; Lam, J. W. Y.; Hong, Y.; Wang, J.; Faisal, M.; Sung, H. H. Y.; Williams, I. D.; Tang, B. Z. Chem. Sci. 2011, 2, 1850-1859. (†contributed equally).

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(6) Thiol-Yne Click Polymerization: Regio- and Stereoselective Synthesis of Sulfur-Rich Acetylenic Polymers with Controllable Chain Conformations and Tunable Optical Properties
Liu, J. Z.; Lam, J. W. Y.; Jim, C. K. W.; Ng, J. C. Y.; Shi, J.; Su, H.; Yeung, K. F.; Hong, Y.; Faisal, M.; Yu, Y.; Wong, K. S.; Tang, B. Z. Macromolecules 2011, 44, 68-79.

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(5) Hyperbranched Conjugated Polysiloles: Synthesis, Structure, Aggregation-Enhanced Emission, Multicolor Fluorescent Photopatterning, and Superamplified Detection of Explosives
Liu, J. Z.; Zhong, Y.; Lam, J. W. Y.; Lu, P.; Hong, Y.; Yu, Y.; Yue, Y.; Faisal, M.; Sung, H. H. Y.; Williams, I. D.; Wong, K. S.; Tang, B. Z. Macromolecules 2010, 43, 4921-4936.

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(4) A Superamplification Effect in the Detection of Explosives by a Fluorescent Hyperbranched Poly(silylenephenylene) with Aggregation-Enhanced Emission Characteristics
Liu, J. Z.; Zhong, Y.; Lu, P.; Hong, Y.; Lam, J. W. Y.; Faisal, M.; Yu, Y.; Wong, K. S.; Tang, B. Z. Polym. Chem. 2010, 1, 426-429.

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(3) Acetylenic Polymers: Syntheses, Structures, and Functions
Liu, J. Z.; Lam, J. W. Y.; Tang, B. Z. Chem. Rev. 2009,109, 5799-5867.

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(2) Exploration of Effective Catalysts for Diyne Polycyclotrimerization, Synthesis of an Ester-Functionalized Hyperbranched Polyphenylene, and Demonstration of Its Utility as a Molecular Container with Implication for Controlled Drug Delivery.
Liu, J. Z.; Zhang, L.; Lam, J. W. Y.; Jim, C. K. W.; Yue, Y.; Deng, R.; Hong, Y.; Qin, A.; Sung, H. H. Y.; Williams, I. D.; Jia, G.; Tang, B. Z. Macromolecules 2009,42,7367-7378.

(1) Hyperbranched poly(silylenephenylenes) from polycyclotrimerization of A(2)-type diyne monomers: Synthesis, characterization, structural modeling, thermal stability, and fluorescent Patterning.
Liu, J. Z.; Zheng, R.; Tang, Y.; Häussler, M.; Lam, J. W. Y.; Qin, A.; Ye, M.; Hong, Y.; Gao, P.; Tang, B. Z. Macromolecules 2007, 40, 7473-7486.




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